Effect of antipsychotic drugs and orthostatic hypotension on the risk of falling in schizophrenic patients Ferinauli Ferinauli,1Sari Narulita,1Yoanita Hi

Ferinauli, Ferinauli and Narulita, Sari and Hijriati, Yoanita (2021) Effect of antipsychotic drugs and orthostatic hypotension on the risk of falling in schizophrenic patients Ferinauli Ferinauli,1Sari Narulita,1Yoanita Hi. Journal of Public Health Research, 10. ISSN eISSN 2279-9036

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Abstract

Abstract Background: Management of schizophrenia using psychopharmaceuticals requires a long-term treatment. The use of antipsychotic drugs can cause the occurrence of orthostatic hypotension, which leads to the risk of falling in patients. The aim of this study is to determine the effect of the use of antipsychotic drugs and orthostatic hypotension on the risk of falling in schizophrenic patients. Design and Methods: This study used a descriptive design with 53 respondents. Data were analyzed using the contingency coefficient correlation and Spearman Rank test methods. Results: The results of the first study showed no positive effect between the use of antipsychotics on orthostatic hypotension in schizophrenic patients. In addition, a contingency coefficient correlation (C) of 0.199 and p-value of 0.335 (p>0.05) was obtained. The results of the second study showed that there was a significant positive effect between orthostatic hypotension on the risk offalling in schizophrenic patients with a value of r = 0.483 and a pvalue of 0.000 (p0.001). Conclusion: It was suggested that the development of this study’s result is needed for further research in dealing with theincidence of orthostatic hypotension in order to prevent or reducethe risk of falling in schizophrenic patients

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